The protection offered by the Mobile WristRX
is provided by the special padding that cushions the bottom (or heel) of your palm. This is the part of the hand that the weight of your arm rests upon when typing. Without cushioning, this weight causes damage over time. Sure, you could make a practice of keyboarding without letting your palms rest on the desk, but that merely shifts more strain to your elbows or your arm muscles.
The cushioning in the Mobile WristRX feels almost like a gel mat when they are in use, but with less give and less resilience. Instead of sinking into the cushion deeply and then it expanding again when you lift your hands, the cushioning in the Mobile WristRX tends to conform to your hands, protecting them from being impacted on the hard surfaces of your desk.
Another advantage that the Mobile WristRX has over a gel wrist pad is that since it is connected to your hand, it is wherever you need it, whenever you need it. It's right where you need it when you're using your keyboard and it's right where you need it when you're using your mouse. You don't have to compromise and settle for a mouse pad with a gel wrist pad attached. You can use a huge mousing surface designed for extreme gamers, and still have protection for your wrists.
I find the Mobile WristRX to be comfortable, even on my hands (larger than average). It seems that one size does, indeed, fit most - and since it's reversible, you can use it on either hand. I am not only a gamer, but a computer programmer as well; I find that two of these take a great deal of strain out of typing and mousing for long hours, and would readily recommend them to gamers who spend a lot of time at work, play or just hanging out in MySpace or IM'ing their friends.