Over the Hedge looks about as good as you can expect on a DS. The textures and models look like a really good N64 title, in other words slightly pixelated but overall good. Cut-scenes come in two flavors, fully pre-rendered movies with fairly good voice acting and still images with a lot of reading. Either way, they do a good job of pushing the story along, though the movies are, naturally, a bit more enjoyable. The game also uses the two screens fairly well. Not only does the top screen show off the the turtle's eye-view of the world you are scurrying around in, but the bottom screen gives you a top-down, bird's eye-view. Done similar to the bottom screen of Mario 64 for the DS, except in 3D, this bottom screen made it easy to sneak around prowling cats and dogs.
As I said above, the voice acting is fairly dead on. Though they are not the all-star-cast from the film, the actors do fairly good imitations, but the only place those voices show up are in the movies. Other sound effects, like dogs barking, cats growling, etc., are okay but sound just a bit too fake.